WHO Ramps-up Ebola Vaccine Trials
Vocabulary
Direction: Read each word and let the student repeat it.
preliminary
[prɪˈlɪmɪnəri] (adjective)
– happening before a more important action or event
ex.The preliminary tests showed that this mission could be a success.
preliminary
[prɪˈlɪmɪnəri] (adjective)
– happening before a more important action or event
ex.The preliminary tests showed that this mission could be a success.
trial
[traɪəl] (noun)
– the process of testing the ability, quality or performance of somebody/something, especially before you make a final decision about them
ex.The new drug is undergoing several trials before being put on the market.
[traɪəl] (noun)
– the process of testing the ability, quality or performance of somebody/something, especially before you make a final decision about them
ex.The new drug is undergoing several trials before being put on the market.
efficacy
[efɪkəsi] (noun)
– the ability of something, especially a drug or a medical treatment, to produce the results that are wanted
ex.We have to do more research in order to evaluate the efficacy and safety of the treatment.
[efɪkəsi] (noun)
– the ability of something, especially a drug or a medical treatment, to produce the results that are wanted
ex.We have to do more research in order to evaluate the efficacy and safety of the treatment.
ramp up
[ræmp ʌp] (phrasal verb)
– to make something increase in amount
ex.The company quickly ramped up production to meet the demand.
[ræmp ʌp] (phrasal verb)
– to make something increase in amount
ex.The company quickly ramped up production to meet the demand.
immunity
[ɪˈmjuːnəti] (noun)
– the body’s ability to avoid or not be affected by infection and disease; the state of being protected from something
ex.Officials of the state receive certain privileges and immunities.
[ɪˈmjuːnəti] (noun)
– the body’s ability to avoid or not be affected by infection and disease; the state of being protected from something
ex.Officials of the state receive certain privileges and immunities.
Article
Direction: Read each paragraph and let the student repeat it.
WHO Ramps-up Ebola Vaccine Trials
The World Health Organization has announced – what it calls -an ambitious plan to have hundreds of thousands of doses of Ebola vaccines available by next June. The WHO announced Friday it is speeding up clinical trials of the two leading vaccine candidates.WHO Assistant Director-General Dr. Marie Paule Kieny unveiled a three-part strategy to fast-track Ebola vaccine development and distribution.The first phase involves the two most promising vaccine candidates – one from GlaxoSmithKline and the other from the Canadian government known as VSV. Almost immediately after the preliminary results of Phase One trials are available in December, Kieny says, a combination of Phase Two and Phase Three trials will begin.“Without waiting for the results of Phase One – so the key trials which are currently ongoing – all is put in place by all partners to start efficacy trials in affected countries in December, as early as December 2014,” she said.Besides the two leading vaccine candidates, five other potential vaccines are in development. Kieny stressed that none of the candidates can cause the Ebola Virus Disease.The second part of the WHO strategy concerns stepped-up manufacture of the vaccines.“The pharmaceutical companies developing these vaccines, as well as the ones which are a little bit longer in the development path, are committing to ramping-up the production capacity to millions of doses to be available in 2015 – with hundreds [of] thousands ready in the first half of next year.”For this to happen, she said, licensing and regulatory issues must be resolved quickly.Part three of the strategy requires community engagement. Kieny said it’s important for local communities to own the immunization process to help eliminate any myths or fears that may arise about the vaccines.“Work should be scaled-up urgently in partnership between local communities, national governments, NGOs and international organizations to have this happen,” she said.Vaccine trials currently are underway in the United States, Britain and Mali. Trials will begin soon in Switzerland, Germany, Gabon and Kenya. The trials are expected to show just how many doses of a vaccine may be needed to ensure immunity. So, although hundreds of thousands of doses may be available by the end of June, it’s not clear just how many people could be vaccinated.Kieny said, “Of course, as we accelerate in a matter of weeks a process that typically takes years, we are ensuring that safety remains a top priority with production speed and capacity a close second.”But since the trials will take weeks and not years, all the possible side effects may not be known right away.The WHO official said vaccines must be part of an overall Ebola strategy.“Vaccines are not a magic bullet. But when ready they may be a good part of the effort to turn the tide of this epidemic.”The number of doses actually needed would depend on how much progress has been made in controlling the epidemic. Greater progress could mean fewer doses. Vaccine doses not used would be stockpiled. Health care workers would be among the first to receive the vaccine.Whichever vaccines prove reliable, they must be stored in extreme cold – minus 80 degrees Celsius — to prevent degradation. So storage units must be part of distribution plans. Also, the price per dose is not known at this time.Dr. Kieny said that Ebola plans are constantly evolving and could easily be adjusted in the coming weeks.Financing could come from donor countries, as well as MSF, or Doctors Without Borders, the World Bank and the GAVI Alliance.
Questions
Direction: Ask the students the questions, and give the answers.
- 1When does the WHO hope to have hundreds of thousands of doses of Ebola vaccines available?
- 2When are the efficacy trials going to start?
- 3In total, how many vaccines are being developed?
- 4In what countries are vaccine trials already underway?
- 5How must vaccines be stored?
Next June.
In December.
“Besides the two leading vaccine candidates, five other potential vaccines are in development.” (Seven)
Vaccine trials currently are underway in the United States, Britain and Mali.
“Whichever vaccines prove reliable, they must be stored in extreme cold – minus 80 degrees Celsius.”
Discussion
Direction: Discuss the topics.
- 1What do you think about the health system in your country?
- 2Do you think the world is doing enough to stop the spread of Ebola?
- 3What do you do to stay healthy?
Follow-up question1: Have you ever been admitted to a hospital in your country?
Follow-up question2: If so, what did you think of the services.
Follow-up question3: Have you ever been admitted to a hospital in another country?
Follow-up question2: If so, what did you think of the services.
Follow-up question3: Have you ever been admitted to a hospital in another country?
Follow-up question1: What additional steps do you think can be taken in order to stop the virus from spreading?
Follow-up question2: Are you worried about Ebola?
Follow-up question3: Do you think that the low standard of living in most African countries has helped Ebola spread? Why or why not?
Follow-up question2: Are you worried about Ebola?
Follow-up question3: Do you think that the low standard of living in most African countries has helped Ebola spread? Why or why not?
Follow-up question1: Do you think that you are leading a healthy lifestyle? Why or why not?
Follow-up question2: Do you think it is important for children to take up a sport? Why or why not?
Follow-up question3: What sports did/do you practice?
Follow-up question2: Do you think it is important for children to take up a sport? Why or why not?
Follow-up question3: What sports did/do you practice?
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